跨骨多普勒脉动性指数变化与动脉瘤下arachnoid出血后的临床结果的相关性

相关实验视频

Updated: Jan 7, 2026

Point of Care Transcranial Color-Coded Duplex Ultrasound of the Middle Cerebral Artery

Point of Care Transcranial Color-Coded Duplex Ultrasound of the Middle Cerebral Artery

Published on: August 9, 2024

Jason J Chang¹, David Kepplinger², Siqi Wei²

¹Department of Critical Care Medicine, MedStar Washington Hospital Center, Washington, DC, USA; Department of Neurology, Georgetown University Medical Center, Washington, DC, USA.

Journal of the neurological sciences

|December 24, 2025

概括

中脑动脉 (MCA) 中脉动指数 (PI) 的变化与脑下关节出血 (SAH) 患者的不良结果有关. 增加PI变异性预测临床结果更差,突出其在SAH监测中的重要性.

科学领域:

神经学神经学
神经临界护理是指神经临界护理.
医疗成像医学成像

背景情况:

下关节出血 (SAH) 的监测通常使用跨内多普勒 (TCD) 平均流速 (MFV) 和脉动性指数 (PI).
在中脑动脉 (MCA) 中评估PI和MFV对于理解与延迟脑缺血 (DCI) 和临床结果的关联至关重要.

研究的目的:

评估MCA中的PI和MFV变量之间的关系,以及它们对SAH患者的DCI和临床结果的预测价值.
确定特定的PI和MFV参数,这些参数是SAH后不良临床结果的重要预测指标.

主要方法:

六年来对268名SAH患者进行了回顾性分析.
编制串行PI和MFV值,包括每日PI最大绝对变化 (AbsΔPI).
多变量逻辑回归和AUC-ROC分析,以确定不良临床结果的预测因素 (定义为3个月修改的兰金尺度) 和DCI.

主要成果:

在PI,MFV和人口统计学变量中,预测临床结果的AUC-ROC为0.84.
每日PI (AbsΔPI) 的最大绝对变化,年龄较大,亨特·赫斯得分和费舍尔得分是不良临床结果的重要预测因素.
没有任何MFV变量与临床结果有显著的关联.

结论:

在MCAs中的PI变化与SAH患者的临床结果有显著的关联.
每增加0.1倍的PI变异性,就相当于1.4倍的不良临床结果的几率.
需要进一步的研究来证实这些发现及其临床影响.

关键词:

大脑的自我调节.平均流速的平均流速.结果结果的结果.冲动性指数是指冲动性的指数.甲状腺下下垂体出血经骨多普勒检测结果

更多相关视频

Analysis of Cerebral Vasospasm in a Murine Model of Subarachnoid Hemorrhage with High Frequency Transcranial Duplex Ultrasound

Analysis of Cerebral Vasospasm in a Murine Model of Subarachnoid Hemorrhage with High Frequency Transcranial Duplex Ultrasound

Published on: June 3, 2021

Functional Transcranial Doppler Ultrasound for Monitoring Cerebral Blood Flow

Functional Transcranial Doppler Ultrasound for Monitoring Cerebral Blood Flow

Published on: March 15, 2021

相关概念视频

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...