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Updated: Jan 7, 2026

Combining 3D Magnetic Force Actuator and Multi-Functional Fluorescence Imaging to Study Nucleus Mechanobiology
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Published on: July 5, 2022

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耐药癌细胞显示核机械转导的增加和机械向的YAP受调节的脆弱性

Miao Huang1, Yinong Chen2, Chenyu Liang1

  • 1Department of Mechanical and Aerospace Engineering, Herbert Wertheim College of Engineering, University of Florida, Gainesville, FL, 32610, USA; UF Health Cancer Center, University of Florida, Gainesville, FL, 32610, USA.

Biomaterials
|December 24, 2025
PubMed
概括

耐药肺癌细胞对机械力更为敏感. 针对这种机械敏感性,特别是YAP核定位,提供了一种消除耐药癌细胞和改善治疗结果的新策略.

关键词:
在CRISPR/Cas9工程内源蛋白标签上药物耐药性 药物耐药性 药物耐药性耐药癌细胞 (DRCs) 是一种抗药性癌细胞.耐药性持久细胞 (DTPs) 是一种耐药性持久细胞.机械向癌症的脆弱性 机械向癌症的脆弱性机械生物学 机械生物学核力学 核力学 核力学光学质询的审讯方式是的相关蛋白 (YAP) 是的

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