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Updated: Jan 7, 2026

Mouse Footpad Inoculation Model to Study Viral-Induced Neuroinflammatory Responses
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基础科学和病原发生学

Christopher Lee1, Stefan Wendt1, Ada J Lin1

  • 1University of British Columbia, Vancouver, BC, Canada.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 24, 2025
PubMed
概括

这项研究使用了人类多能干细胞衍生的神经圈来建模阿尔茨海默病 (AD) 并调查阿波利波蛋白E (APOE) 变体的作用. 结果显示,APOE ε2提供了对粉样β诱导的神经退行症的保护,突出了其治疗潜力.

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