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Updated: Jan 7, 2026

Mouse Footpad Inoculation Model to Study Viral-Induced Neuroinflammatory Responses
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基础科学和病原发生学

Aya Arrar1,2,3, Madison R Longmuir1,2,3, Kate M Onuska2,3,4

  • 1Schulich School of Medicine & Dentistry, London, ON, Canada.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 24, 2025
PubMed
概括

在新型人性化小鼠模型中,Apolipoprotein E4 (ApoE4) 基因型加速阿尔茨海默病 (AD) 病理,包括粉样β和积累,神经退行和认知缺陷. 这项研究强调了ApoE4在AD病变发生过程中的重要作用.

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