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Updated: Jan 7, 2026

Continuous Fluorescence-Based Endonuclease-Coupled DNA Methylation Assay to Screen for DNA Methyltransferase Inhibitors
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在物质使用障碍中的DNA甲基化酶机制:系统性审查

Margot Diringer1, Mathieu Bruggeman1, Pierre-Eric Lutz1

  • 1Centre National de la Recherche Scientifique, Université de Strasbourg, Institut des Neurosciences Cellulaires et Intégratives UPR 3212, F-67000 Strasbourg, France.

Neurobiology of disease
|December 24, 2025
PubMed
概括

表观遗传变化,特别是DNA甲基化,在物质使用障碍 (SUD) 中起着至关重要的作用. 在动物模型上的研究表明,这些变化可以双向地影响SUD的表现,突出潜在的治疗点.

关键词:
关于成的行为模型.通过DNA甲基化.在DNA甲基转移酶中.药物使用障碍 药物使用障碍泰特酶 (tet) 是一种酶.

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