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酸化Ser500作为一个调整转换到eEF-2K的转换器来激活

Amanda L Bohanon1, Luke S Browning1, Andrea Piserchio2

  • 1Interdisciplinary Life Sciences Graduate Program, the University of Texas, Austin, TX, 78712.

The Journal of biological chemistry
|December 24, 2025
PubMed
概括

细胞延长因子-2激酶 (eEF-2K) 活性是通过Ca2+/calmodulin (CaM) 结合和酸化在T348和S500调节的. 这些修改稳定了活性构造,增强了CaM的响应能力和整合细胞信号.

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