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Updated: Jan 7, 2026

Assays for Validating Histone Acetyltransferase Inhibitors
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Assays for Validating Histone Acetyltransferase Inhibitors

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辅助因子在人体基因素脱乙酶8:功能要求和药物发现的机会

Paula M Garcia-Franco1, F Javier Falco-Marti2, Hajar Jeblaoui3

  • 1Institute of Biocomputation and Physics of Complex Systems (BIFI), Universidad de Zaragoza, 50018, Zaragoza, Spain; Certest Biotec S.L., 50840, San Mateo de Gallego, Zaragoza, Spain.

International journal of biological macromolecules
|December 24, 2025
PubMed
概括

海斯脱乙酶8 (HDAC8) 是智力障碍和癌症的药物标. 研究人员描述了HDAC8的稳定性和辅因子相互作用,揭示了无状态作为潜在的药物发现目标.

关键词:
结合平衡的结合平衡.热量测量方法热量测量方法符合形态平衡的平衡基因组脱乙酶 8 8 基因组脱乙酶分子动力学模拟的模拟.这是一种依赖的蛋白质.

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