临床表现 临床表现
Olufisayo Oluyinka Elugbadebo1,2, Olusegun Baiyewu3, Hephzibah Oyedapo-Ishola4
1College of Medicine, University of Ibadan, Ibadan, Nigeria.
Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 24, 2025
概括
痴呆症的行为和心理症状 (BPSD) 在认知障碍的老年人中很常见. 抑郁症和食欲的变化是频繁的,造成了显著的护理人员痛苦,特别是在痴呆症组.
科学领域:
- 老年学是一门学科.
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
背景情况:
- 痴呆症的行为和心理症状 (BPSD) 是痴呆症的组成部分,导致护理人员的痛苦并影响死亡率.
- 在发展中国家,对患有认知障碍的老年人BPSD的研究有限.
- 这项研究调查了印第安纳波利斯-伊巴丹痴呆症项目幸存者的BPSD.
研究的目的:
- 评估尼日利亚伊巴丹最年长人口中BPSD的患病率和严重程度.
- 评估不同认知诊断组中与BPSD相关的护理人员痛苦水平.
- 确定特定的BPSD及其对该人口群中的护理人员的影响.
主要方法:
- 印第安纳波利斯-伊巴丹痴呆症项目的伊巴丹分支机构的幸存者重新检查 (注册1992/2001,重新检查2021/2022).
- 使用CERAD神经心理电池进行神经心理评估.
- 基于DSM IV TR和NIA标准 (正常认知,MCI,痴呆症) 的诊断;使用神经精神病 inventory问卷 (NPI-Q) 评估的BPSD.
主要成果:
- 评估了135名幸存者 (平均年龄为92.5岁):46.1%的认知正常,32.4%的MCI,21.5%的痴呆症.
- 抑郁症是MCI (27.3%) 和痴呆症 (34.5%) 组中最常见的BPSD.
- 痴呆症组的BPSD严重程度最高 (4.20 ± 4.49);食欲变化最严重. 在痴呆症组 (2.21 ± 4.14) 中,护理人员的痛苦是最高的,食欲变化和抑郁症引起了最多的痛苦.
结论:
- 抑郁症和相关的护理人员痛苦在老年人中所有认知诊断群体中普遍存在.
- 这些发现强调了需要针对发展中国家认知障碍老年人抑郁症和其他BPSD进行有针对性的干预.
- 解决护理人员的痛苦对于管理这种脆弱人群中的BPSD至关重要.
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