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相关概念视频

Infection01:20

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When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
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Urinary Tract Infection II: Pathophysiology01:25

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The pathophysiology of urinary tract infections (UTIs) encompasses several progressive stages, beginning with bacterial colonization and culminating in potential systemic complications if untreated. UTIs are primarily initiated by bacteria, such as Escherichia coli, which often originate from the gastrointestinal tract and migrate to the urinary system through the periurethral area. This migration can occur via several routes, including improper hygiene practices, sexual activity, or...
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Cystic fibrosis (CF), an autosomal recessive disorder, significantly affects the function of exocrine glands. This genetically inherited disease is characterized by the production of thick and sticky mucus, which can severely affect various organs and systems in the body.
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Stages of infection describe what happens to a susceptible host once a pathogen invades the human body. The stages of infection are incubation, prodromal, illness, stage of decline, and convalescence. The incubation stage is the period from exposure to a pathogen until symptoms start. The infected person is unaware of impending illness as the pathogens grow and multiply within the body. The duration may vary depending on the type of infection. The incubation period of measles averages ten to...
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基础科学和病原发生学

Enid Swatson1, Whitney Wharton1, Danielle D Verble1

  • 1Emory University, Atlanta, GA, USA.

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概括
此摘要是机器生成的。

诸如高血压和动脉硬等心血管疾病标志物与衰老成年人的认知功能较差有关. 这些关联在种族群体之间可能有所不同,这凸显了对多样化的研究和个性化的健康策略的需求.

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科学领域:

  • 神经学 神经学
  • 心脏病学 心脏病学
  • 老年学是一门学科.

背景情况:

  • 心血管疾病 (CVD) 是美国老年人的主要健康问题.
  • 高血压,高胆固醇和生活方式因素是心血管疾病和阿尔茨海默病 (AD) 的风险因素.
  • 慢性高血压有助于动脉硬和大脑血流受损,与认知能力下降有关.

研究的目的:

  • 为了研究血管健康和认知功能之间的关系,在一个多样化的群体认知正常的个体有患AD的风险.
  • 检查动脉硬和血压如何与各种认知领域相关.

主要方法:

  • 利用了来自E2和ASCEND纵向研究中年到老年人的数据,他们的父母有AD病史.
  • 进行认知电池评估口语流,视觉空间能力和执行功能.
  • 测量了动脉硬度和大动脉血压的脉冲波速度 (PWV),随后进行了线性回归分析.

主要成果:

  • 在非西班牙裔白人 (NHW) 参与者中,较高的PWV与语言流性和记忆任务的表现较差相关.
  • 系统性血压与NHW和黑人/非裔美国人 (B/AA) 个体的数字跨度性能下降有关.
  • 透气血压和脉压在NHW参与者中显示出与认知表现的关联,但在B/AA个体中不一致.

结论:

  • 血压升高和动脉硬与多个领域的认知功能下降有关.
  • 血管和认知关系可能因种族而异,这表明普遍的诊断和治疗方法是不够的.
  • 未来的研究必须优先考虑各种人群,以了解疾病机制,并制定公平的预防和治疗策略.