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Updated: Jan 7, 2026

Mouse Footpad Inoculation Model to Study Viral-Induced Neuroinflammatory Responses
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基础科学和病原发生学

Brian Carson1, Josephine Chu1, Devaraj V Chandrashekar2

  • 1Keck Graduate Institute, Claremont, CA, USA.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 24, 2025
PubMed
概括

减少肝脏的LDL受体相关蛋白1 (LRP1) 会增加大脑中的粉样β (Aβ). 肝脏LRP1对于清除外围Aβ至关重要,并且可能是阿尔茨海默病 (AD) 的治疗点.

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