[前列腺癌在中国和全球的流行病学特征]
1Office for Cancer Registry, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.
Zhonghua zhong liu za zhi [Chinese journal of oncology]
|December 24, 2025
概括
前列腺癌的负担在全球范围内有所不同,发达地区的发病率更高,较不发达地区的死亡率更高. 时间趋势显示,中国的发病率正在上升,而美国的发病率正在下降.
科学领域:
- 流行病学 流行病学
- 全球健康 全球健康
- 在瘤学瘤学.
背景情况:
- 前列腺癌代表着一个重要的全球健康挑战.
- 了解疾病负担的分布和趋势对于公共卫生战略至关重要.
研究的目的:
- 分析前列腺癌疾病负担的全球分布和时间趋势.
- 调查社会经济因素,特别是人类发展指数 (HDI) 和前列腺癌负担之间的关系.
主要方法:
- 利用GLOBOCAN 2022数据进行区域,国家和HDI水平的疾病负担分析.
- 运用斯皮尔曼相关性和受限制的立方线来评估HDI负担关系.
- 分析了使用五大洲癌症发病率 (CI5) 数据和年平均百分比变化 (AAPC) 的时间趋势 (1988-2017).
主要成果:
- 在2022年,全球前列腺癌发病率为1,468,000例 (ASIR:29.4/10) 和397,000例死亡 (ASMR:7.3/10).
- 观察到的显著差异:在非常高的HDI地区最高的ASIR (57.7/10),在低的HDI地区最高的ASMR (14.0/10).
- 从1988年到2017年,前列腺癌发病率在中国增加最多 (AAPC=7.7%),在美国减少最多 (AAPC=-1.4%).
结论:
- 前列腺癌是一个巨大的全球负担,具有独特的区域模式.
- HDI指出的社会经济发展与前列腺癌发病率和死亡率的变化密切相关.
- 考虑到发育水平,有针对性的公共卫生干预措施是必要的,以管理全球前列腺癌负担.
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