在老年人群中,相互排斥的肌肉健康状况之间的动态转换和相关风险因素
Wen-Hui Fang1,2, Tao-Chun Peng1,2, Yuan-Ping Chao1,2
1Division of Family Medicine, Department of Family and Community Medicine, Tri-Service General Hospital, School of Medicine, College of Medicine, National Defense Medical University, Taipei, Taiwan.
BMC geriatrics
|December 24, 2025
概括
患有肌肉功能低下 (dynapenia) 的老年人比患有肌肉质量低 (presarcopenia) 的老年人更有可能恢复到强壮的状态. 早期干预至关重要,以防止易受伤害的老年人患上肉症的进展.
科学领域:
- 老年学是一门学科.
- 肌肉生理学 肌肉生理学
- 衰老研究研究 衰老研究
背景情况:
- 标志着肌肉质量和功能的损失的萨尔科佩尼亚,从前来的低肌肉量 (前萨尔科佩尼亚) 或肌肉质量差 (肌肉质量差) (肌肉质量差) 的状态发展起.
- 过渡途径和从这些独特的sarcopenic前状态的恢复潜力仍然不完全理解.
研究的目的:
- 在老年人中,研究纵向肌肉健康的转变,从先前缩症和动脉缩症到缩症.
- 确定影响肉症进展和恢复到强壮状态的因素.
主要方法:
- 居住在社区的65岁以上的成年人每年接受肌肉质量,功能和身体组成的评估.
- 参与者被分为强壮的,前性 (仅仅是低肌肉质量),性 (仅仅是肌肉功能差) 或性 (两种).
- 生存分析和回归模型检查过渡概率和相关决定因素.
主要成果:
- 准皮症与进展为皮症的风险显著增加 (HR=4.20).
- 动力衰竭与更高的恢复到强壮状态的可能性相关 (HR=4.18).
- 较高的身体脂肪百分比和脂肪与肌肉比率预测了肉类的过渡,而较大的肌肉质量,手握强度和白蛋白水平预测了恢复.
结论:
- 前肉症和动力症代表肌肉健康下降的不同途径,对肉症的发展和恢复的预后不同.
- 针对sarcopenic和dynapenic个体的有针对性的干预措施对于预防sarcopenia和促进健康衰老至关重要.
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