吸烟与糖尿病神经病变之间的关联:系统性审查和元分析
Sana Bader1, Sanah Hasan2,3, Dianna J Magliano4,5
1School of Public Health and Preventive Medicine, Faculty of Medicine, Nursing, and Health Sciences, Monash University, Melbourne, VIC, Australia. sbad0008@student.monash.edu.
吸烟显著增加了糖尿病神经病变的风险,特别是外围神经病变. 这一系统性审查强调了进一步研究糖尿病患者神经病变病因的必要性.
科学领域:
- 内分泌学和新陈代谢学
- 神经学 神经学
- 公共卫生 公共卫生
背景情况:
- 糖尿病神经病变是一种糖尿病的常见并发症.
- 吸烟是众所周知的各种健康并发症的危险因素.
研究的目的:
- 系统地审查吸烟与糖尿病神经病变风险之间的联系的证据.
- 专门评估患有糖尿病的个体的外围神经病变风险.
主要方法:
- 在MEDLINE,EMBASE,SCOPUS和CENTRAL数据库中搜索到2024年8月.
- 包括横截面,病例控制和队列研究,评估吸烟和糖尿病神经病变.
- 使用ROBINS-E工具评估研究偏差.
主要成果:
- 包括75篇关于228,699名糖尿病患者的文章.
- 队列研究显示,外围神经病变的风险增加 (RR 1.28).
- 分析表明所有糖尿病神经病变类型的风险增加 (OR 1.29-1.48).
结论:
- 吸烟与糖尿病神经病变,特别是外围神经病变的风险更高有关.
- 需要进一步的研究,以了解糖尿病的神经病变的发病因子,以预防.
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