临床表现 临床表现
See Ann Soo1, Jermyn Z See1, Nav Vij1
1Neurowyzr Pte Ltd, Singapore, Singapore, Singapore.
Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 24, 2025
概括
数字大脑功能屏幕 (DBFS) 与MoCA相比,在检测轻度认知障碍方面表现出强大的构造有效性和高的测试重试可靠性. 这使得DBFS成为监测认知衰退的可靠工具.
科学领域:
- 神经科学是一个神经科学.
- 医疗技术 医疗技术 医学技术
- 认知科学 认知科学
背景情况:
- 数字大脑功能屏幕 (DBFS) 是一种用于早期检测和监测轻度认知障碍 (MCI) 的数字工具.
- 虽然与MoCA相比,DBFS缺乏其构造有效性和测试-重新测试可靠性的正式验证.
- 这项研究旨在确定DBFS的这些心理特征.
研究的目的:
- 评估DBFS与MoCA之间的构造有效性.
- 评估DBFS的测试-重新测试可靠性.
- 确认DBFS作为认知评估的有效和可靠工具.
主要方法:
- 157名 (10-81岁) 个人接受了DBFS和MoCA评估.
- 36名参与者在305天的中位数间隔后完成了第二次DBFS评估.
- 使用部分斯皮尔曼等级相关性分析了构造有效性和测试-重新测试可靠性,控制年龄,性别和教育.
主要成果:
- DBFS总分数与MoCA总分数有显著的相关性 (p < 0.001).
- 在相应的DBFS和MoCA域之间发现了强烈的正相关性 (p <0.05),表明了良好的构造有效性.
- DBFS的试验-重试可靠性很高,斯皮尔曼的 ρ = 0.65 (p < 0.001).
结论:
- DBFS有效地测量了预期的认知构造,并随着时间的推移显示出高可靠性.
- 这些发现证实DBFS是一种实用,可扩展和高效的工具,用于检测和监测早期认知障碍.
- DBFS适合在各种医疗保健环境中部署用于认知查.
相关概念视频
Chronic Kidney Disease II: Clinical Manifestations
520
Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
520
Coronary Artery Disease III: Clinical Manifestations
299
Coronary Artery Disease (CAD) is a primary health risk worldwide, leading to significant morbidity and mortality. The condition arises from the buildup of atherosclerotic plaques within the coronary arteries, resulting in diminished blood supply to the heart muscle.The clinical manifestations of CAD vary widely, from asymptomatic stages to severe, life-threatening conditions. Understanding these manifestations is crucial for early diagnosis and effective management.Angina Pectoris: The Warning...
299
Endocarditis II: Clinical Features of Infective Endocarditis
364
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
364
Heart Failure III: Clinical Manifestations
436
Heart failure (HF) manifests primarily as dyspnea, fatigue, and fluid retention, resulting in peripheral and pulmonary edema. Symptoms may vary depending on which ventricle is more affected, left or right.Left-Sided Heart FailureAlso known as left ventricular failure, this condition results from the left ventricle's inability to fill or eject sufficient blood into the systemic circulation. It leads to pulmonary congestion, which occurs when the left ventricle fails to eject blood effectively...
436
Gastroesophageal Reflux Disease II: Clinical Features and Management
652
Gastroesophageal reflux disease, or GERD, is a persistent medical condition that affects many individuals worldwide. Its clinical manifestations can vary greatly, making diagnosis and management challenging for healthcare professionals. The following is a comprehensive overview of the clinical manifestations, assessment, and management strategies for GERD.
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
652
Hypertension III: Clinical Manifestations and Diagnostic Studies
437
Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
437


