Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Blood Studies for Cardiovascular System I: Cardiac Biomarkers01:20

Blood Studies for Cardiovascular System I: Cardiac Biomarkers

749
Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
749
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers01:19

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers

516
Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
516

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Convergent Network Localization of Brain Stimulation Targets for Trait Anxiety.

The American journal of psychiatry·2026
Same author

Lesion network localization of depression in multiple sclerosis.

Nature. Mental health·2026
Same author

Atrophy in preclinical Alzheimer's disease maps to a network that predicts longitudinal decline.

Molecular psychiatry·2026
Same author

Connectivity- vs Scalp-Based Targeting of Accelerated Transcranial Magnetic Stimulation for Depression: A Randomized Clinical Trial.

JAMA psychiatry·2026
Same author

Contusion Volume is a Cross-cohort Predictor of Delayed Seizures after Traumatic Brain Injury.

medRxiv : the preprint server for health sciences·2026
Same author

A prognostic human brain network for diffuse midline glioma.

Nature·2026

相关实验视频

Updated: Jan 7, 2026

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
07:20

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

Published on: January 28, 2014

37.1K

生物标志物 生物标志物

Soyoung Lee1, Sheena R Baratono1, Grace T Burt1

  • 1Brigham and Women's Hospital, Boston, MA, USA.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 24, 2025
PubMed
概括
此摘要是机器生成的。

阿尔茨海默病 (AD) 脑缩在没有认知障碍的个体中与不同的大脑网络有关. 识别这些网络有助于了解早期AD病理生理学和风险分层.

更多相关视频

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

7.9K
Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans
08:14

Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans

Published on: April 28, 2023

702

相关实验视频

Last Updated: Jan 7, 2026

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
07:20

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

Published on: January 28, 2014

37.1K
Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

7.9K
Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans
08:14

Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans

Published on: April 28, 2023

702

科学领域:

  • 神经科学是一个神经科学.
  • 医疗成像医学成像
  • 老年学是一门学科.

背景情况:

  • 阿尔茨海默病 (AD) 病理学,包括粉样β (Aβ) 积累,在认知衰退之前.
  • 在临床前的AD中,Aβ相关的大脑缩和特定的认知网络之间的关系尚不清楚.
  • 了解早期网络水平缩对于AD病理生理学和风险分层至关重要.

研究的目的:

  • 为了确定在临床前的AD中是否有Aβ相关的大脑缩,将其映射到不同的认知网络中.
  • 为了确定与早期AD的客观和主观认知变化相关的特定大脑网络.
  • 探索缩网络映射的实用性,以了解临床前AD.

主要方法:

  • 分析了1778名认知不受损的老年人 (65-85岁) 的结构性MRI和粉样蛋白βPET扫描.
  • 使用顶点通用的一般线性模型创建个性化缩图.
  • 使用规范的人类连接组估计缩模式的功能连接性.
  • 线性回归以将缩连接性与客观 (PACC) 和主观 (CFI) 认知得分联系起来.

主要成果:

  • 在临床前的AD中,针对客观和主观认知变化确定了不同的大脑网络.
  • 缩模式连接到上时环与客观认知障碍 (PACC) 有关.
  • 与中关联的缩模式与主观认知障碍 (CFI) 有关.

结论:

  • 缩网络映射成功地确定了与临床前AD中过渡性认知变化相关的独特脑网络.
  • 这些发现增强了对早期AD病理生理学的理解.
  • 这种方法对于在临床前阿尔茨海默病中定位早期认知症状是有价值的,从阿尔茨海默病痴呆症扩展其应用.