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临床表现 临床表现

Joana Emilia Senger1, Luiza Santos Machado2, Maiele Dornelles Silveira3

  • 1Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.

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概括
此摘要是机器生成的。

长期的COVID可能会影响全球认知分数,特别是在受教育程度较低的人群中. 高等教育可能会提供对长期COVID神经效应的认知弹性.

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科学领域:

  • 神经科学是一个神经科学.
  • 公共卫生 公共卫生
  • 认知科学 认知科学

背景情况:

  • 长期COVID是SARS-CoV-2感染后的一种持续性疾病,呈现出各种症状,包括神经效应.
  • 了解长期COVID对认知功能的影响对于公共卫生战略至关重要.
  • 教育成就是影响认知储备和性的已知因素.

研究的目的:

  • 为了调查COVID对成年人神经心理表现的影响时间.
  • 检查教育水平 (高低) 在长期COVID的认知影响中的作用.
  • 根据教育和长期COVID状态,识别认知结果的潜在差异.

主要方法:

  • 巴西波多阿莱格的社区成年人被分为四组:控制低教育,控制高教育,长期COVID低教育和长期COVID高教育.
  • 神经心理学评估包括迷你精神状态检查 (MMSE),轨迹测试 (TMT-B) 和韦克斯勒记忆量表 (WMS-R).
  • 分析差异 (ANOVA) 和克鲁斯卡尔·沃利斯测试用于分析群体差异,统计显著性设置为p < 0.05.

主要成果:

  • 总共有122名参与者 (平均年龄59.6岁,73.8%的女性) 进行了分析.
  • 与对照高教育组相比,在对照低教育组观察到较低的MMSE分数 (p=0.007).
  • 长期COVID-低教育组的MMSE分数也明显低于控制高教育组 (p=0.009),表明教育对认知表现的影响,但没有发现特定的长期COVID对其他认知领域的影响.

结论:

  • 教育成就显著影响认知储备和抵御长期COVID的神经表现的弹性.
  • 高等教育可能会防止与长期COVID相关的认知衰退.
  • 虽然长期的COVID与全球认知得分的降低有关,但特定的认知领域并不是唯一脆弱的;对低教育人口的支持对大脑健康至关重要.