Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Chronic Kidney Disease II: Clinical Manifestations01:24

Chronic Kidney Disease II: Clinical Manifestations

520
Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
520
Coronary Artery Disease III: Clinical Manifestations01:30

Coronary Artery Disease III: Clinical Manifestations

299
Coronary Artery Disease (CAD) is a primary health risk worldwide, leading to significant morbidity and mortality. The condition arises from the buildup of atherosclerotic plaques within the coronary arteries, resulting in diminished blood supply to the heart muscle.The clinical manifestations of CAD vary widely, from asymptomatic stages to severe, life-threatening conditions. Understanding these manifestations is crucial for early diagnosis and effective management.Angina Pectoris: The Warning...
299
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

364
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
364
Heart Failure III: Clinical Manifestations01:26

Heart Failure III: Clinical Manifestations

436
Heart failure (HF) manifests primarily as dyspnea, fatigue, and fluid retention, resulting in peripheral and pulmonary edema. Symptoms may vary depending on which ventricle is more affected, left or right.Left-Sided Heart FailureAlso known as left ventricular failure, this condition results from the left ventricle's inability to fill or eject sufficient blood into the systemic circulation. It leads to pulmonary congestion, which occurs when the left ventricle fails to eject blood effectively...
436
Gastroesophageal Reflux Disease II: Clinical Features and Management01:29

Gastroesophageal Reflux Disease II: Clinical Features and Management

652
Gastroesophageal reflux disease, or GERD, is a persistent medical condition that affects many individuals worldwide. Its clinical manifestations can vary greatly, making diagnosis and management challenging for healthcare professionals. The following is a comprehensive overview of the clinical manifestations, assessment, and management strategies for GERD.
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
652
Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

Hypertension III: Clinical Manifestations and Diagnostic Studies

437
Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
437

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Relative importance of blood-based biomarkers for Alzheimer's disease-specific neurodegeneration and cognitive decline.

The journal of prevention of Alzheimer's disease·2026
Same author

Reorganization of brain-autonomic integration in alcohol use disorder.

Progress in neuro-psychopharmacology & biological psychiatry·2026
Same author

Fosfomycin as Oral Transition Therapy Versus Continued Intravenous β-Lactams for Complicated Urinary Tract Infections Caused by Extended-Spectrum β-Lactamase-Producing Enterobacterales: A Multicenter, Open-Label, Randomized Controlled Trial.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
Same author

Quality of mental health care among insured patients in an Indonesian psychiatric hospital.

BMC health services research·2026
Same author

Performance and Cost-Efficiency of an MPT64 Assay for Detecting <i>Mycobacterium tuberculosis</i> Complex in a Setting With Frequent Nontuberculous Mycobacteria Isolation.

Journal of Korean medical science·2026
Same author

Clinical Approaches to <i>Clostridioides difficile</i> Infection Management: Insights From a Nationwide Survey of Korean Physicians.

Journal of Korean medical science·2026

相关实验视频

Updated: Jan 7, 2026

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
07:50

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

Published on: September 20, 2018

16.4K

临床表现 临床表现

Eun Jin Yoon1,2, Heejung Kim2,3, Jun-Young Lee2,3

  • 1Seoul National University, Seoul, Korea, Republic of (South).

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 25, 2025
PubMed
概括

患有amnestic轻度认知障碍 (aMCI) 和多种行为症状的个体在特定的大脑区域增加了粉样蛋白沉积. 这表明疾病处于更先进的阶段,并强调评估轻度行为障碍 (MBI) 风险分层的实用性.

更多相关视频

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
04:44

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

20.7K
Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from S&#233;zary Syndrome Patients for Transcriptomic Profiling
09:08

Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling

Published on: October 14, 2021

6.1K

相关实验视频

Last Updated: Jan 7, 2026

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
07:50

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

Published on: September 20, 2018

16.4K
Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
04:44

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

20.7K
Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from S&#233;zary Syndrome Patients for Transcriptomic Profiling
09:08

Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling

Published on: October 14, 2021

6.1K

科学领域:

  • 神经科学是一个神经科学.
  • 神经学 神经学
  • 老年学是一门学科.

背景情况:

  • 之前的研究表明,在有多种轻度行为障碍 (MBI) 领域症状的amnestic轻度认知障碍 (aMCI) 患者中,阿尔茨海默病进展的风险更高.
  • 这项研究调查了MBI亚组与aMCI个体的早期粉样蛋白沉积之间的关联.

研究的目的:

  • 为了确定aMCI患者中的特定MBI亚组是否与早期粉样β (Aβ) 沉积有关.
  • 探索MBI,粉样蛋白负担和aMCI中的认知功能之间的关系.

主要方法:

  • 121名aMCI患者和23名认知正常 (CU) 个体接受了18F-florbetaben (FBB) PET扫描.
  • 使用转换算法评估MBI,将aMCI参与者分为无症状,情绪失调和复杂的组.
  • 在群体之间进行了FBB PET标准化吸收值比率 (SUVR) 地图的voxel-wise比较,对年龄和性别进行控制.

主要成果:

  • 复杂的MBI组与CU个体相比,在前皮质,下皮质和角皮质中显示出更高的区域FBB SUVR.
  • 复杂组的粉样蛋白阳性aMCI患者的认知分数比无症状组的认知分数低.
  • 在MBI子组之间,没有发现全球或区域粉样蛋白沉积的显著差异.

结论:

  • 在aMCI中,多个同时出现的MBI症状与增加的区域性粉样蛋白沉积和认知衰退有关,表明疾病更为晚期.
  • MBI评估可以帮助对MCI患者进行风险分层.
  • 这些发现强调了行为症状对于了解MCI疾病进展的重要性.