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Updated: Jan 7, 2026

Functional Assessment of BRCA1 variants using CRISPR-Mediated Base Editors
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由基编辑器引起的非目标RNA编辑热点

Michelle Shmuel-Eidelman1, Roni Cohen-Fultheim1, Eli Eisenberg2

  • 1Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat Gan 5290002, Israel; The Institute of Nanotechnology and Advanced Materials, Bar-Ilan University, Ramat Gan 5290002, Israel.

Molecular therapy : the journal of the American Society of Gene Therapy
|December 25, 2025
PubMed
概括

这项研究引入了一种新方法来检测基因编辑器,基因编辑工具的意外RNA编辑. 它可以识别特定的基因和易受这些非目标编辑的区域,这对于开发更安全的基因疗法至关重要.

关键词:
在RNA编辑指数上.亚丁基编辑器的编辑器基础编辑 基础编辑细胞酶基编辑器编辑器基因组编辑 基因组编辑目标之外的活动活动.

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