Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Blood Studies for Cardiovascular System I: Cardiac Biomarkers01:20

Blood Studies for Cardiovascular System I: Cardiac Biomarkers

749
Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
749
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers01:19

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers

516
Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
516

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

In Vivo Assessment of Placental Structure and Perfusion in Late-Gestation Pregnancies and Their Association With Fetal Growth.

NMR in biomedicine·2026
Same author

Lifespan Trajectories of the Brain's Functional Complexity Characterized by Multiscale Sample Entropy.

NeuroImage·2026
Same author

Cognitive reserve against vascular contributions to cognitive impairment and dementia: A scoping review.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same author

Role of 2-phenylethanol in regulating population density and biocontrol efficacy of Scheffersomyces spartinae W9 via quorum sensing.

International journal of food microbiology·2026
Same author

Transcriptomic and Metabolomic Analyses Reveal Color Variation and Taste Formation of Different Radish Sprouts.

Journal of agricultural and food chemistry·2026
Same author

Multimodal Free-Water Imaging Links Cardiometabolic Risk to Periarterial Dysfunction and Amyloid Accumulation in Early Alzheimer's.

Research square·2026
Same journal

Multimorbidity burden and patterns associated with DeepBrainNet-derived brain-age gap in dementia-free older adults: A community-based study.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Reply to "Shifting the emphasis of brain health literacy from individuals to systems to reduce inequalities".

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Shifting the emphasis of brain health literacy from individuals to systems to reduce inequalities.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Correlates and predictors of self-efficacy among dementia caregivers: D-CARE findings.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

What should convince a clinician of disease modification in Alzheimer's disease clinical trials?

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Primary cilia-extracellular vesicle crosstalk in Alzheimer's disease: Emerging mechanisms and biomarker potential.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
查看所有相关文章

相关实验视频

Updated: Jan 7, 2026

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
07:20

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

Published on: January 28, 2014

37.1K

生物标志物 生物标志物

Colleen Pappas1, Christopher E Bauer1, Valentinos Zachariou1

  • 1University of Kentucky, Lexington, KY, USA.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 25, 2025
PubMed
概括
此摘要是机器生成的。

血脑屏障 (BBB) 水交换率 (kw) 的增加与老年人随着时间的推移恶化的白质超强度 (WMHs) 有关. 这表明BBB功能障碍可能会导致脑血管疾病的进展.

更多相关视频

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

7.9K
Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans
08:14

Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans

Published on: April 28, 2023

702

相关实验视频

Last Updated: Jan 7, 2026

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
07:20

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

Published on: January 28, 2014

37.1K
Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

7.9K
Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans
08:14

Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans

Published on: April 28, 2023

702

科学领域:

  • 神经成像是一种神经成像.
  • 脑血管疾病研究研究
  • 认知障碍研究 认知障碍研究

背景情况:

  • 脑血管疾病 (CVD) 影响认知功能,导致认知障碍和痴呆症 (VCID).
  • 血脑屏障 (BBB) 完整性越来越被认为是心血管疾病的一个因素.
  • 磁共振成像 (MRI) 标志物,如白质超强度 (WMHs) 和自由水 (FW) 是已知的心血管疾病指标.

研究的目的:

  • 为了研究BBB水交换率 (kw),BBB功能的衡量标准,以及大约2.5年的WMH和FW变化之间的关系.
  • 探索基线BBB功能如何与脑血管损伤标志物的进展有关.

主要方法:

  • 68名老年人使用扩散准备的伪连续动脉旋转标记 (DP-pCASL) 进行神经成像,以测量BBB水交换率 (kw),脑血流量 (CBF) 和动脉传输时间 (ATT).
  • 在基线和随访时使用MRI (FLAIR和扩散权重成像) 量化WMH体积和白质FW.
  • 混合效应模型分析了基线DP-pCASL测量和WMH或FW变化之间的关联,控制年龄,性别和内体积.

主要成果:

  • 较高的基线BBB水交换率 (kw) 预测了随着时间的推移WMH的增加,尽管在基线上没有关系.
  • 较高的基线脑血流 (CBF) 与基线较少的WMH相关,但与纵向变化无关.
  • 动脉传输时间 (ATT) 与WMHs没有显著的关联.
  • 较高的kw与较低的FW截面相关,但这在纵向上没有持续.
  • 在基线或随着时间的推移,CBF和ATT与FW无关.

结论:

  • 初步发现表明BBB的水交换率 (kw) 与WMH和基线FW的纵向变化有关.
  • 在BBB中增加的水交换可能会增加对白质损伤的易感性.
  • 需要进一步的研究,以充分阐明BBB效率对脑血管健康的影响.