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移动工具箱 (MTB) 中的新西班牙语认知测试增强了西班牙语使用者的阿尔茨海默氏症和相关痴呆症 (ADRD) 研究. 这些文化敏感的措施支持早期诊断和在不同人群中识别风险因素.

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科学领域:

  • 神经科学和认知心理学:专注于开发和验证认知评估工具.
  • 老年学:在老年人群中解决认知健康和阿尔茨海默病和相关痴呆症 (ADRD).
  • 卫生信息学:利用技术进行远程研究管理和数据收集.

背景情况:

  • 在大规模研究中,西班牙语认知评估的可用性有限,特别是在老年人中.
  • 迫切需要采取文化包容性措施,以促进早期诊断,并确定阿尔茨海默病和相关痴呆症 (ADRD) 的可修改风险因素.
  • 移动工具箱 (MTB) 提供简短,敏感的神经和行为功能测量,与REDCap和MyCap集成,用于远程研究.

研究的目的:

  • 在移动工具箱 (MTB) 中引入新开发的西班牙语认知测试.
  • 介绍西班牙语单词含义测试的校准研究结果.
  • 展示平台对西班牙语人口认知研究的实用性.

主要方法:

  • 七个英语MTB认知措施由母语人士改编成西班牙语,具有文化敏感的刺激更新.
  • 使用对1620名西班牙语成年人的校准研究开发西班牙语单词含义项目库.
  • 使用拉什模型进行西班牙语单词含义测试,以确保与英语版本的一致性.

主要成果:

  • 现在MTB包括语言,执行功能,关联记忆,情节性记忆,工作记忆和处理速度的西班牙语认知测试.
  • 西班牙语单词含义测试校准完善了项目库,删除了88个不合适的项目,导致515个项目.
  • 西班牙语单词含义测试的难度参数从-1.896到2.074不等,使用Rasch模型进行校准.

结论:

  • 通过技术和测量进步,MTB有效地解决了认知评估方面的挑战.
  • 该平台适用于各种研究环境,包括大规模,临床和制药研究.
  • 英语和西班牙语测试的可用性提高了MTB支持不同人群的研究能力,帮助ADRD研究.