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临床表现 临床表现

Duong Huynh1, NaZanin Mirshahi2, Emilirgh Wong2

  • 1BrainCheck Inc., Austin, TX, USA.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 25, 2025
PubMed
概括

像BrainCheck评估 (BC-Assess) 这样的数字认知评估 (DCA) 显示出中等到良好的可靠性和有效性. 这些证据支持BC-Assess作为一种有效的认知查工具,与传统方法相比.

科学领域:

  • 神经科学是一个神经科学.
  • 数字健康数字健康
  • 认知科学 认知科学

背景情况:

  • 数字认知评估 (DCA) 为早期痴呆症检测提供了一个有希望的途径.
  • 脑检查评估 (BC-Assess) 是一种基于证据的DCA工具,旨在为医疗保健提供者进行快速和可靠的认知障碍评估.
  • 之前的研究表明,BC-Assess有效地区分正常认知,轻度认知障碍和痴呆症.

研究的目的:

  • 为了评估BC-Assess工具的测试-重新测试可靠性.
  • 为了确定与传统的纸和笔神经心理测试相比,BC-Assess的并发有效性.
  • 进一步验证BC-Assess作为可靠的认知查工具.

主要方法:

  • 从美国四个临床地点招募了529名参与者.
  • 测试重复测试可靠性在60名参与者的子集上进行了评估,评估间隔超过7天.
  • 在68名参与者的子集中评估了并发有效性,将BC-Assess领域 (记忆,执行功能,注意力,处理速度) 与传统测试 (HVLT,Stroop,Trail Making,WAIS) 相比较.
  • 类内相关系数 (ICC) 和皮尔森的相关系数分别用于可靠性和有效性分析.

主要成果:

  • BC-Assess显示测试复试可靠性中等至良好,ICC值在0.69-0.89 (p < .001) 之间.

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  • 同时有效性显示了BC-Assess认知领域评估及其纸和笔对应的中等相关性 (r = 0.31-0.57,p <= .01).
  • 这些结果表明数字和传统评估方法之间的一致性和可比性.

    • 结论:

    • 脑检查提供可靠和有效的认知功能评估.
    • BC-Assess的性能与传统的纸和笔测试相美.
    • 这些发现强化了BC-Assess作为有效的认知查工具的实用性.