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基础科学和病原发生学

Anil R Wadhwani1, David C Goldberg2, Philip L De Jager3

  • 1Department of Neurology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 25, 2025
PubMed
概括

差异性DNA甲基化 (DNAm) 可以区分初级与年龄相关的病 (PART) 和阿尔茨海默病 (AD). 使用DNAm的机器学习工具准确地预测了PART与PART的对比. 在AD和未确定病例中分层,揭示了PART的独特生物程序和认知性.

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