临床表现 临床表现
Rafi Haddad1,2, Elena Tsoy3, Judith Aharon-Peretz2,4
1Global Brain Health Institute, University of California, San Francisco, San Francisco, CA, USA.
Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 25, 2025
概括
基于平板电脑的认知评估工具脑健康评估 (TabCAT-BHA) 有效地识别了阿拉伯语说话的以色列人的认知障碍. 这种文化适应的工具具有很高的准确性,有助于早期检测和解决医疗保健差异.
科学领域:
- 神经学 神经学
- 老年学是一门学科.
- 公共卫生 公共卫生
背景情况:
- 痴呆症在中东和北非是一个重大的公共卫生挑战,特别影响阿拉伯语人口.
- 由于缺乏文化和语言适应的评估,以色列阿拉伯语人士存在认知医疗差异.
- 需要简短的,不依赖语言的认知措施来弥合这一差距.
研究的目的:
- 评估基于平板电脑的认知评估工具脑健康评估 (TabCAT-BHA) 的阿拉伯版本的并发有效性和区别准确性.
- 评估TabCAT-BHA在以色列阿拉伯语老年人中检测认知障碍的实用性.
主要方法:
- 57名认知障碍 (MCI或痴呆症) 的老年人和39名认知正常的人完成了阿拉伯语TabCAT-BHA.
- 认知障碍的参与者还完成了标准的口语记忆,视觉记忆,视觉空间技能和处理速度的纸和笔测试.
- 使用后勤回归,ROC曲线和皮尔森相关性来评估歧视准确性和并发有效性,并根据年龄,性别和教育进行调整.
主要成果:
- 在检测认知障碍方面,TabCAT-BHA表现出极好的区分精度 (AUC = 0.97,灵敏度 = 0.93,特异性 = 0.79).
- 在特定的TabCAT-BHA子测试和相应的标准认知测试 (例如,带有视觉记忆的观鸟,带有口头记忆的最爱) 之间发现了强烈的相关性.
- 匹配子测试显示了与所有检查的认知领域的中度关联,反映了执行功能的作用.
结论:
- 阿拉伯语TabCAT-BHA是一个有效和有效的工具,用于识别阿拉伯语说话的以色列人的认知障碍.
- 这些发现支持使用TabCAT-BHA来解决这一群体的认知医疗差异.
- 未来的研究将专注于完善规范,并确认其在轻度认知障碍中早期发现疾病的有用性.
相关概念视频
01:24Chronic Kidney Disease II: Clinical Manifestations
520
Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
520
01:30Coronary Artery Disease III: Clinical Manifestations
299
Coronary Artery Disease (CAD) is a primary health risk worldwide, leading to significant morbidity and mortality. The condition arises from the buildup of atherosclerotic plaques within the coronary arteries, resulting in diminished blood supply to the heart muscle.The clinical manifestations of CAD vary widely, from asymptomatic stages to severe, life-threatening conditions. Understanding these manifestations is crucial for early diagnosis and effective management.Angina Pectoris: The Warning...
299
01:25Endocarditis II: Clinical Features of Infective Endocarditis
364
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
364
01:26Heart Failure III: Clinical Manifestations
436
Heart failure (HF) manifests primarily as dyspnea, fatigue, and fluid retention, resulting in peripheral and pulmonary edema. Symptoms may vary depending on which ventricle is more affected, left or right.Left-Sided Heart FailureAlso known as left ventricular failure, this condition results from the left ventricle's inability to fill or eject sufficient blood into the systemic circulation. It leads to pulmonary congestion, which occurs when the left ventricle fails to eject blood effectively...
436
01:29Gastroesophageal Reflux Disease II: Clinical Features and Management
652
Gastroesophageal reflux disease, or GERD, is a persistent medical condition that affects many individuals worldwide. Its clinical manifestations can vary greatly, making diagnosis and management challenging for healthcare professionals. The following is a comprehensive overview of the clinical manifestations, assessment, and management strategies for GERD.
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
652
01:30Hypertension III: Clinical Manifestations and Diagnostic Studies
437
Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
437