痴呆症护理研究和心理社会因素
Zihan Wang1, Qiumin Qu1, Ling Gao1
1The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 25, 2025
概括
深呼吸练习可能会减缓阿尔茨海默病 (AD) 患者的认知衰退,并减少精神病症状. 这项为期48周的研究表明,每天深呼吸是阿尔茨海默病的潜在新治疗方法.
科学领域:
- 神经学 神经学
- 老年学是一门学科.
- 精神病学是一个精神病学.
背景情况:
- 众所周知,深呼吸可以缓解情绪并改善血液循环.
- 新兴研究表明,深呼吸可能会增强淋巴系统.
- 深呼吸对阿尔茨海默病 (AD) 的具体影响仍未确定.
研究的目的:
- 为了研究深呼吸练习在管理轻度至中度阿尔茨海默病的有效性.
- 评估深呼吸对AD患者认知功能,日常生活活动和精神症状的影响.
主要方法:
- 一项为期48周的盲人临床试验,涉及40名参与者 (年龄在50-80岁) 患有轻度至中度的AD.
- 参与者被随机分配到深呼吸组 (每天15个周期,每天3次) 或常规治疗组.
- 主要终点包括ADAS-cog,CIBIC-plus,ADCS-ADL和NPI得分的变化,使用多变量逻辑回归分析.
主要成果:
- 深呼吸组在阿尔茨海默氏病评估量表-认知子量表 (ADAS-cog) 评分 (p=0.033) 和神经精神科目录 (NPI) 评分 (p=0.013) 中显著改善.
- 在阿尔茨海默氏病合作研究-日常生活活动量表 (ADCS-ADL) 或临床采访基础的变化印象与护理人员输入量表 (CIBIC-plus) 分数中,在两组之间没有发现显著差异.
- 迷你精神状态检查 (MMSE) 的分数在深呼吸和传统治疗组之间也没有显著差异.
结论:
- 在48周内,深呼吸练习导致轻度至中度AD患者的认知功能下降速度较慢.
- 与传统治疗组相比,深呼吸组的患者表现出较轻微的精神症状.
- 每天深呼吸是治疗阿尔茨海默病的一种有希望的非药物治疗方法.
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