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Updated: Jan 7, 2026

Refined Murine Model of Idiopathic Pulmonary Fibrosis
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Published on: June 17, 2025

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功能通路的交换式甲基化区分了慢性肺炎和异常性肺纤维化

Katherine H Shutta, Yichen Huang, Vincent L Carey

    medRxiv : the preprint server for health sciences
    |December 25, 2025
    PubMed
    概括

    DNA甲基化差异可以区分慢性阻塞性肺病 (COPD) 和异常性肺纤维化 (IPF). 这项研究确定了肺组织中的特定DNA甲基化模式或"开关",这表明它在疾病发展中的作用以及COPD和IPF的潜在新治疗点.

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