针对儿科急性淋巴细胞白血病的行为健康干预措施:范围审查
Carolyn R Bates1, Sydney M Gibson2, Peter R Johnson3
1Department of Pediatrics, University of Kansas Medical Center, University of Kansas Cancer Center, Kansas City, KS, United States.
Frontiers in oncology
|December 25, 2025
概括
小儿急性淋巴细胞白血病 (ALL) 患者的行为健康干预措施各不相同,但需要更严格的研究. 未来的研究应该集中在更大的试验上,以改善ALL儿童的治疗结果和长期健康.
科学领域:
- 儿科瘤学 儿科瘤学
- 行为科学 行为科学
- 健康 结果 研究 研究 结果
背景情况:
- 急性淋巴细胞白血病 (ALL) 是一种常见的儿童癌症,存活率高.
- 饮食,活动和睡眠等健康行为显著影响儿科ALL患者的治疗耐受性和晚期影响.
- 现有的行为干预措施旨在改善接受ALL治疗的儿童和青少年的即时和长期健康结果.
研究的目的:
- 对接受ALL治疗的儿童和青少年进行行为健康干预措施的范围审查.
- 评估针对立即和长期健康结果的干预措施的范围.
- 识别有关干预有效性和研究严谨性的文献上的差距.
主要方法:
- 根据JBI证据综合手册和PRISMA-ScR指南进行范围审查.
- 在PubMed,Elsevier和Web of Science数据库中进行全面的文献搜索.
- 查,数据提取,并通过多个审查员对儿童ALL治疗中的行为健康促进干预措施进行评估.
主要成果:
- 在157篇选的全文文章中,有86篇文章符合纳入标准.
- 干预主要集中在体力活动/运动 (36),程序性困扰 (24),营养 (8) 和症状管理 (6) 上.
- 在研究中的出版日期,方法和干预组件中发现了显著的变化.
结论:
- 关于儿童ALL行为干预的文献广泛,但缺乏深度.
- 许多研究受到小样本规模的限制,仍处于可行性阶段.
- 需要进行更大,更严格的试验来评估干预的有效性,并改善儿科ALL幸存者的治疗结果.
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