一张皮层功能网络的地图,它调解了自然主义导航
Tianjiao Zhang1,2, Emily X Meschke2, Jack L Gallant1,2
1Helen Wills Neuroscience Institute, University of California, Berkeley; Berkeley, CA 94720, USA.
bioRxiv : the preprint server for biology
|December 25, 2025
概括
现实世界的导航涉及感知,规划和行动. 这项研究绘制了大脑的地图.
科学领域:
- 神经科学是一个神经科学.
- 认知科学 认知科学
背景情况:
- 现实世界的导航整合了感知,规划和运动行为.
- 之前的研究表明大皮层的广泛参与,但缺乏围膜和前额叶区域的详细表征.
- 了解完整的导航网络对于认知神经科学至关重要.
研究的目的:
- 绘制和描述整个皮质网络,以支持自然导航.
- 研究与导航相关的大脑区域的功能性质和组织.
- 提供主动导航神经基础的统一描述.
主要方法:
- 功能磁共振成像 (fMRI) 用于记录在自然导航任务期间的大脑活动.
- 使用带状回归来安装高维编码模型,分析了28,134个特征.
- 分析了大脑活动数据,以确定与导航有关的功能上不同的皮质区域.
主要成果:
- 一个由11个功能上不同的皮质区域组成的网络支持自然导航.
- 这一网络包括五个前额叶,三个顶层和三个视觉皮层区域.
- 编码模型分析显示,这些区域的感知输入转化为行动输出,沿着功能梯度组织.
结论:
- 该研究确定了用于现实世界导航的综合性皮质网络.
- 这11个区域的组织是为了处理从感知到决策到行动的信息.
- 这些发现为导航网络组织提供了统一的观点,并为未来的研究提供了目标.
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