Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Elastin is Responsible for Tissue Elasticity01:12

Elastin is Responsible for Tissue Elasticity

3.0K
Elastic fiber contains the protein elastin along with lesser amounts of other proteins and glycoproteins. The main property of elastin is that it will return to its original shape after being stretched or compressed. Elastic fibers are prominent in elastic tissues found in skin and the elastic ligaments of the vertebral column.
Ligaments and tendons are made of dense regular connective tissue, but in ligaments not all fibers are parallel. Dense regular elastic tissue contains elastin fibers and...
3.0K
Cell-matrix's Response to Mechanical Forces01:13

Cell-matrix's Response to Mechanical Forces

3.4K
In animal cells, the extracellular matrix allows cells within tissues to withstand external stresses and transmits signals from the outside of the cell to the inside. The extracellular matrix is extensive, and its composition varies between different types of tissues. For example, the reticular fibers and ground substance make up the ECM in loose connective tissue, while collagen and bone minerals make up the ECM of bone tissue. 
Anchoring junctions mechanically attach a cell to the...
3.4K
Tension Response at Adherens Junctions01:26

Tension Response at Adherens Junctions

3.4K
The adherens junctions that anchor cells together are multi-protein complexes that dynamically adapt to mechanical stimuli such as tensile forces and shear stress. Mechanosensory proteins in these junctions can sense such mechanical stimuli and undergo a shift in their conformation, resulting in an altered function — a process called mechanotransduction.
α-Catenin as a Mechanosensory Protein
The α-catenin of adherens junctions is an allosteric protein with three VH (vinculin...
3.4K
Cell Motility through Blebbing01:16

Cell Motility through Blebbing

2.4K
Blebs are a type of membrane protrusion formed by the internal hydrostatic pressure of the cytoplasm. Blebs are observed in several cell types, including fibroblasts, immune cells, and single-celled organisms like the amoeba. The primary function of blebs is cell locomotion and apoptosis, but they are also found during necrosis and cell division. The life cycle of a bleb comprises an initiation phase followed by the expansion and retraction phases.
Blebbing Through the Matrix
In multicellular...
2.4K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Reinforcement learning for adaptive control of phenotypically heterogeneous bacterial populations.

bioRxiv : the preprint server for biology·2025
Same author

Physical traits of supercompetitors in cell competition.

Journal of the Royal Society, Interface·2025
Same author

Cell Geometry Limits Bacterial Metabolic Efficiency.

bioRxiv : the preprint server for biology·2025
Same author

Mechanistic basis for non-exponential bacterial growth.

bioRxiv : the preprint server for biology·2025
Same author

Catalytic growth in a shared enzyme pool ensures robust control of centrosome size.

eLife·2025
Same author

Anisotropic Cell Shape and Motion Coordinate Hindbrain Neuropore Morphogenesis.

bioRxiv : the preprint server for biology·2024

相关实验视频

Updated: Jan 7, 2026

Equibiaxial Stretching Device for High Magnification Live-Cell Confocal Fluorescence Microscopy
08:41

Equibiaxial Stretching Device for High Magnification Live-Cell Confocal Fluorescence Microscopy

Published on: June 13, 2025

1.0K

通过局部张力重塑来学习上皮质弹性.

Sadjad Arzash1, Shiladitya Banerjee1

  • 1School of Physics, Georgia Institute of Technology, Atlanta, GA 30332.

bioRxiv : the preprint server for biology
|December 25, 2025
PubMed
概括
此摘要是机器生成的。

表皮组织通过一种新型模型记住机械应力,改变其刚性并对遥远的刺激做出反应. 这种物理学习允许可编程组织类风湿学.

更多相关视频

Live Cell Imaging during Mechanical Stretch
07:42

Live Cell Imaging during Mechanical Stretch

Published on: August 19, 2015

10.9K
Probing Cell Mechanics with Bead-Free Optical Tweezers in the Drosophila Embryo
08:23

Probing Cell Mechanics with Bead-Free Optical Tweezers in the Drosophila Embryo

Published on: November 2, 2018

7.9K

相关实验视频

Last Updated: Jan 7, 2026

Equibiaxial Stretching Device for High Magnification Live-Cell Confocal Fluorescence Microscopy
08:41

Equibiaxial Stretching Device for High Magnification Live-Cell Confocal Fluorescence Microscopy

Published on: June 13, 2025

1.0K
Live Cell Imaging during Mechanical Stretch
07:42

Live Cell Imaging during Mechanical Stretch

Published on: August 19, 2015

10.9K
Probing Cell Mechanics with Bead-Free Optical Tweezers in the Drosophila Embryo
08:23

Probing Cell Mechanics with Bead-Free Optical Tweezers in the Drosophila Embryo

Published on: November 2, 2018

7.9K

科学领域:

  • 生物物理学的生物物理.
  • 细胞生物学 细胞生物学
  • 材料科学 材料科学 材料科学

背景情况:

  • 表皮组织在响应机械力时动态重塑.
  • 了解组织如何存储机械记忆是一个关键的挑战.

研究的目的:

  • 使用一个活跃的顶点模型,研究表皮板中的机械记忆.
  • 确定历史依赖的机械敏感重塑的后果.

主要方法:

  • 开发了一种用于上皮层的活跃顶点模型.
  • 整合了一个局部,机械敏感的张力重塑规则.
  • 分析了组织对局部和循环变形的反应.

主要成果:

  • 局部应力永久重编程全球剪切模量,可通过重塑速率调节.
  • 组织表现出远程机械记忆,远程刺激反应由先前事件调节.
  • 循环变形程序组织属性,包括辅助波桑比率.

结论:

  • 表皮机械在无监督的物理学习下运行.
  • 机械敏感重塑率控制可编程组织尺度的类风学.