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Updated: Jan 7, 2026

Identification of Mediators of T-cell Receptor Signaling via the Screening of Chemical Inhibitor Libraries
08:49

Identification of Mediators of T-cell Receptor Signaling via the Screening of Chemical Inhibitor Libraries

Published on: January 22, 2019

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结合一个共同的抑制剂的细菌和人类糖酶转移酶的结构为选择性治疗提供了信息

Beebee Yusrah Kaudeer1, Jacob M Kirsh1, Katsuhiko Mitachi2

  • 1Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, United States.

bioRxiv : the preprint server for biology
|December 25, 2025
PubMed
概括

研究人员研究了MraY和DPAGT1酶,这些酶对细菌和人类细胞过程至关重要. 他们使用冷EM可视化一种抑制剂APPB,揭示了开发新抗菌和抗癌药物的见解.

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Enzyme Inhibition

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