相关实验视频

Updated: Jan 7, 2026

Imaging of Intracellular ATP in Organotypic Tissue Slices of the Mouse Brain using the FRET-based Sensor ATeam1.03YEMK
11:20

Imaging of Intracellular ATP in Organotypic Tissue Slices of the Mouse Brain using the FRET-based Sensor ATeam1.03YEMK

Published on: December 19, 2019

10.5K

由线粒体膜连接介导的ATP通道驱动活动依赖的葡萄糖代谢

Dengbao Yang1, Gemma Molinaro2, Nadine Nijem2

  • 1Department of Physiology, UT Southwestern Medical Center, Dallas, TX, 75390, USA.

bioRxiv : the preprint server for biology
|December 25, 2025
PubMed
概括

细胞循环退出和神经区分蛋白1 (CEND1) 对于神经元和棕色脂肪细胞的活性依赖葡萄糖代谢至关重要. CEND1将线粒体ATP通到hexokinase I,在高细胞活动期间维持能量生产.

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High-resolution Respirometry to Measure Mitochondrial Function of Intact Beta Cells in the Presence of Natural Compounds12:32

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ATP Energy Storage and Release

ATP is a highly unstable molecule. Unless quickly used to perform work, ATP spontaneously dissociates into ADP and inorganic phosphate (Pi), and the free energy released during this process is lost as heat. The energy released by ATP hydrolysis is used to perform work inside the cell and depends on a strategy called energy coupling. Cells couple the exergonic reaction of ATP hydrolysis with endergonic reactions, allowing them to proceed.
One example of energy coupling using ATP involves a...
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Glucose transporters facilitate the transport of glucose across the cell membrane. In addition to glucose, some glucose transporters can also aid the movement of other hexoses such as fructose, mannose, and galactose.
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Chemiosmosis01:32

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Mitochondrial protein import is powered by two distinct energy sources: ATP hydrolysis and electrochemical potential across the inner membrane. Newly synthesized precursors are bound by cytosolic chaperones of the Hsp70 family, which guide them to the import receptors on the mitochondrial surface. Utilizing the energy of ATP hydrolysis, Hsp70 chaperones transfer these precursors to the TOM receptors on the mitochondrial outer membrane.
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