开发和初步临床可行性为患有喘的儿童提供基于Delphi的有氧运动处方
Ying Zhang1,2, Ze Kong1, Kaixuan Yang2
1Baoding Hospital of Beijing Children's Hospital, Capital Medical University, Baoding, China.
Frontiers in pediatrics
|December 25, 2025
概括
德尔菲开发的一种有氧运动处方对患有喘的儿童来说是安全的和可行的,显示了运动能力和肺功能的潜在改善. 需要进一步的研究来证实小儿喘管理的有效性.
科学领域:
- 儿科肺病学 儿科肺病学
- 运动生理学 运动生理学
- 非药理干预措施 非药理干预
背景情况:
- 儿童喘管理通常依赖于药理疗法.
- 需要基于证据的非药物干预措施,如有氧运动,以改善儿科喘的结果.
- 开发一个临床适用的运动处方需要专家的共识和试点测试.
研究的目的:
- 开发一种临床上适用的有氧运动处方,用于患有喘的儿童,使用两轮的德尔菲共识过程.
- 在前后试点研究中,初步评估此处方的可行性和安全性.
- 为了探索运动能力,肺功能和喘控制的初步变化,以响应运动处方.
主要方法:
- 通过与家长,医疗专业人员和体育康复专家进行半结构化采访,开发了最初的有氧运动处方.
- 该处方通过两轮的德尔菲咨询与儿童肺病学,护理和运动康复领域的17名专家进行了细化.
- 一项为期12周的试点研究涉及15名患有喘的儿童 (6-14岁),评估了可行性,安全性和临床结果,包括6分钟步行距离 (6MWD),螺旋计和儿童喘控制测试 (C-ACT).
主要成果:
- 德尔菲进程取得了高专家共识 (≥75%的同意,权威系数Cr=0.86).
- 试点研究表明100%的招聘率和良好的炼坚持 (2.7次/周).
- 在6MWD (P<0.001),FEV1%预测 (P<0.001) 和C-ACT得分 (P<0.001) 中观察到显著改善,轻度,非破坏性不良事件的发病率低 (13.3%).
结论:
- 德尔菲开发的有氧运动处方在患有喘的儿童中短期使用是可行的,也是安全的.
- 初步发现表明,对运动能力,肺功能和喘控制有潜在的益处.
- 需要对更大的样本大小和受控设计进行进一步的研究,以确认疗效和隔离干预效应.
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