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临床表现 临床表现

Yun Cai1, Rebecca West1, Sharon Sanz Simon1

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概括
此摘要是机器生成的。

招募南亚和中东/北非 (MENA) 个体用于阿尔茨海默病和相关痴呆症 (ADRD) 研究提出了挑战. 萨梅纳队列研究旨在通过制定文化定制的战略来解决这一差距,以便在ADRD研究中获得更好的代表性.

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科学领域:

  • 神经科学是一个神经科学.
  • 公共卫生 公共卫生
  • 遗传学 遗传学 是一个

背景情况:

  • 南亚和中东/北非 (MENA) 人口在阿尔茨海默病和相关痴呆症 (ADRD) 研究中的代表性显著不足.
  • 有证据表明,在不同种族和种族群体中,ADRD风险因素,保护因素和生物标志物概况存在差异.
  • 萨梅纳队伍旨在通过收集这些代表性不足的社区中ADRD患者的后代的纵向数据来弥补这一差距.

研究的目的:

  • 招募来自南亚和MENA社区的参与者参加ADRD研究.
  • 收集关于ADRD风险和保护因素的全面,纵向数据.
  • 为这些人群制定量身定制的预防和治疗策略提供信息.

主要方法:

  • 多方位的招聘策略包括社区外展 (广播,电视,健康营),社交媒体,与社区领导人和组织的合作伙伴关系,以及利用大学网络.
  • 与招聘公司合作进行数字广告和医疗记录挖掘.
  • 对参与者进行查和招募到SAMENA队列中.

主要成果:

  • 在六个月的时间里,大约有300人联系了这项研究;90%的人因种族/种族而没有资格参加.
  • 招募了12名参与者 (8名南亚人,4名MENA人),年龄在45-64岁之间,其中6名女性,8名拥有高级学位.
  • 招募的参与者表现出正常的基线认知功能 (MoCA平均值=28.4,SD=1.5).

结论:

  • 最初的招聘在达到目标南亚和MENA人口方面面临重大挑战.
  • 需要进一步的研究来确定和完善文化定制的招聘策略,通过吸引各种利益相关者.
  • 扩大招聘标准,包括其他痴呆风险因素 (例如肥胖,糖尿病,高血压) 的个人可能是有益的.