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药物开发 药物开发

Xin Huang1,2,3, Jennica Wang1, Yoshiteru Kagawa1,2

  • 1The University of Melbourne, Parkville, VIC, Australia.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 25, 2025
PubMed
概括

在免疫细胞中,ApoE3和ApoE4的Apolipoprotein E (ApoE) 异型抑制了细胞化. 虽然两者都减少了粉样β (Aβ) 的摄取,但ApoE4的Aβ结合较少,可能会启动阿尔茨海默氏症 (AD) 病原发生.

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