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临床表现 临床表现

Camila Rafaela Lazaretti1, Cristiano Aguzzoli1

  • 1Feevale University, Novo Hamburgo, RS, Brazil.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 25, 2025
PubMed
概括
此摘要是机器生成的。

COVID-19可能会导致持久的认知缺陷,影响超过一半的幸存者的记忆和执行功能,无论症状严重程度如何. 长期跟踪对于评估感染后的认知功能至关重要.

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科学领域:

  • 神经学 神经学
  • 传染性疾病 传染性疾病
  • 认知科学 认知科学

背景情况:

  • COVID-19显著影响认知功能,包括更高的皮层能力.
  • 长期认知缺陷在SARS-CoV-2感染后越来越多地被认可.
  • 本综述将轻度至中度和严重的COVID-19病例之间的长期认知障碍进行比较.

研究的目的:

  • 审查和比较不同COVID-19严重程度的个体的长期认知障碍.
  • 为了确定受COVID-19长期影响最严重的认知领域.
  • 为了突出康复后认知缺陷的持续性.

主要方法:

  • 对2020-2024年PubMed索引文章的范围审查.
  • 包括评估COVID-19幸存者的长期认知障碍的研究.
  • 选了20篇文章,并对8篇全文出版物进行了评估.

主要成果:

  • 认知障碍的患病率在急性阶段从61.5% (轻度至中度) 到80% (中度至重度) 之间.
  • 执行功能,工作记忆,语言流性和注意力受到影响最大.
  • 超过50%的人在注意力,记忆力和执行功能方面经历了长期的缺陷;严重的病例在出院数月后出现了持续的问题.

结论:

  • 后COVID-19认知障碍影响所有临床阶段的幸存者的很大一部分.
  • 记忆障碍是观察到的主要长期认知缺陷.
  • 对COVID-19幸存者来说,临床评估和专注于认知功能的长期随访是必不可少的.