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药物开发 药物开发

Hannah R Bulgart1, Miguel A Lopez Perez2, Gianni N Giarrano2

  • 1University of Kentucky, Lexington, KY, USA.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 25, 2025
PubMed
概括

重组TRIM72/MG53 (rhMG53) 蛋白在阿尔茨海默氏症 (AD) 模型中增强了血膜修复. 这种蛋白质治疗减少了由粉样β (Aβ) 引起的神经毒性和细胞死亡,为AD提供了潜在的治疗策略.

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