Jove
Visualize
联系我们

相关概念视频

Blood Studies for Cardiovascular System I: Cardiac Biomarkers01:20

Blood Studies for Cardiovascular System I: Cardiac Biomarkers

746
Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
746
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers01:19

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers

511
Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
511

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Positron emission tomography of neuroinflammation in Down syndrome and Alzheimer's disease: Current status and future perspectives.

Neural regeneration research·2026
Same author

The LELEX initiative to enhance cancer imaging communication: development of a consensus-based structured reporting template and lexicon for general oncologic imaging.

Radiologia brasileira·2026
Same author

Amyloid burden, brain metabolism, and gray matter volume in SuperAgers.

Arquivos de neuro-psiquiatria·2026
Same author

Cryoablation of bone metastases in thyroid and adrenocortical cancers.

Endocrine-related cancer·2026
Same author

Clinical Manifestations.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2025
Same author

Clinical Manifestations.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2025
Same journal

Association of sleep duration with Alzheimer's disease and cognition.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Patient-derived forebrain cortical organoids reveal biphasic tau-MAP6-microtubule axis dysfunction in tauopathy.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Genetic architecture of the limbic white matter microstructure in aging and Alzheimer's Disease.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Greater choroid plexus volume is linked to poor sleep, neurodegeneration, and cognitive deficits in older adults: Evidence from the IGNITE Study.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Plasma-based neurobiological protein biomarkers as predictors of dementia progression: Insights from longitudinal aging study in India - Diagnostic assessment of dementia.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Neuropathology-specific language features in primary progressive aphasia.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
查看所有相关文章
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关实验视频

Updated: Jan 7, 2026

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
07:20

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

Published on: January 28, 2014

37.1K

生物标志物 生物标志物

Chiara Maria Righini1, Larissa Estessi de Souza1, Jean Marques Brizola1

  • 1University of São Paulo Medical School, São Paulo, São Paulo, Brazil.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 25, 2025
PubMed
概括
此摘要是机器生成的。

与大麻 (CBD) 结合的体育炼在唐氏综合征 (DS) 鼠标模型中显示出神经保护作用. 这种组合增强了大脑新陈代谢,这表明了延迟阿尔茨海默病 (AD) 在DS患者中发展的潜在策略.

更多相关视频

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

7.9K
Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans
08:14

Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans

Published on: April 28, 2023

699

相关实验视频

Last Updated: Jan 7, 2026

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
07:20

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

Published on: January 28, 2014

37.1K
Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

7.9K
Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans
08:14

Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans

Published on: April 28, 2023

699

科学领域:

  • 神经科学是一个神经科学.
  • 遗传学 是一个遗传学.
  • 药理学 药理学是指药理学的学科.

背景情况:

  • 唐氏综合征 (DS) 与早期发病的阿尔茨海默病 (AD) 有关,原因是AD相关基因的表达增加,导致神经炎症和细胞死亡.
  • 随着阿尔茨海默氏症患者寿命的不断增长,需要制定策略来延缓阿尔茨海默氏症的进展并提高生活质量.
  • 运动和大麻 (CBD) 以其神经保护性而闻名.

研究的目的:

  • 研究身体炼和CBD单独或组合对唐氏综合征 (DS) 的小鼠模型的影响.
  • 在不同治疗条件下的DS小鼠中使用正子发射断层扫描 (PET) 评估神经炎症和大脑代谢.

主要方法:

  • Ts65Dn三症小鼠被分为四组:对照组,运动组,CBD组和运动+CBD组.
  • 运动包括跑步机活动,每周三次,从2个月到8个月.
  • 从7个月大开始,CBD通过腹腔内 (20毫克/公斤) 给药30天.
  • 用PET成像 ([11C]PK11195和[18F]FDG) 来评估4个月和8个月大脑中的神经炎症和代谢.

主要成果:

  • 在4个月后,运动+CBD组在整个大脑 (WB) 和海马体中显示出明显更高的[11C]PK11195吸收 (神经炎症标志物) 与其他组相比.
  • 在8个月后,CBD和运动+CBD组与对照组和运动组相比,CBD和运动+CBD组的[11C]PK11195吸收增加.
  • 运动+CBD组在WB和海马体中显示,从4到8个月增加了[18F]FDG吸收 (大脑新陈代谢).

结论:

  • 仅仅CBD治疗就引起了显著的质反应,当与体育炼相结合时,这种反应会受到调节.
  • 运动和CBD的组合增强了大脑新陈代谢,这表明一种潜在的神经保护机制可以防止AD在DS的发展.
  • 这种综合方法可能为改善唐氏综合征患者的大脑健康提供了一个有希望的策略.