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临床表现 临床表现

Angel Garcia De La Garza1, Carol A Derby1, Cuiling Wang1

  • 1Albert Einstein College of Medicine, Bronx, NY, USA.

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概括
此摘要是机器生成的。

越来越多的主观认知问题 (SCC) 或自我认知的记忆困难,可能预测未来客观认知表现的下降,通过电话蒙特利尔认知评估 (T-MoCA) 测量. 这一发现强调了随着时间的推移跟踪认知变化的重要性.

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科学领域:

  • 老年学是一门学科.
  • 认知神经科学 认知神经科学
  • 心理学 心理学 心理学

背景情况:

  • 生态瞬间评估 (EMA) 是评估主观认知问题 (SCC) 的一个有价值的工具,而不依赖于记忆回忆.
  • 升高的SCC与认知衰退的风险增加有关,但关于SCC和认知功能的联合轨迹的研究有限.

研究的目的:

  • 使用基于智能手机的EMA,研究主观认知问题 (SCC) 和认知功能的纵向轨迹之间的关联.
  • 探索SCC的不同模式如何与老年人电话蒙特利尔认知评估 (T-MoCA) 评分的变化有关.

主要方法:

  • 利用基于智能手机的EMA进行14天的每日SCC报告和219名社区老年人的年度T-MoCA评估.
  • 采用隐性类线性混合效应模型来识别SCC轨迹,调整人口统计和临床因素.
  • 分析了跨SCC组的T-MoCA轨迹,使用线性混合效应模型与逐块分线来计算学习效应.

主要成果:

  • 确定了两个SCC轨迹组:一个具有持续低的SCC,另一个具有不断增加的SCC.
  • 两组之间没有观察到基线T-MoCA差异,但增加的SCC组在三年后显示T-MoCA得分下降,与低SCC组不同.

结论:

  • 主观认知问题的纵向轨迹与不同的认知表现轨迹有关.
  • 增加SCC可能成为未来客观认知功能的下降的预测因素.