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药物开发 药物开发

Pranav Mishra1,2, Ehsan Esfahani1, Paul Fernyhough1,2

  • 1Division of Neurodegenerative Disorders, St. Boniface Hospital Albrechtsen Research Centre, Winnipeg, MB, Canada.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 25, 2025
PubMed
概括

17β雌二醇 (E2) 通过减轻粉样β (Aβ) 诱导的神经炎症和线粒体功能障碍,保护阿尔茨海默病 (AD) 病理. E2治疗恢复了代谢调节者和增强了神经元功能,这表明AD的治疗潜力.

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