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药物开发 药物开发

Marc Shenouda1,2, Janice Robertson1,2

  • 1University of Toronto, Toronto, ON, Canada.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 25, 2025
PubMed
概括

在临床前模型中,一种新的小分子JRMS有效地降低了交易反应DNA结合蛋白43 (TDP-43) 聚合. 这一发现为神经退行性疾病,如肌缩侧面硬化 (ALS) 和前性痴呆 (FTD) 提供了治疗潜力.

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