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临床表现 临床表现

Berivan Ece1, Emily H Ho1, Sandra Weintraub2

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概括
此摘要是机器生成的。

嗅觉衰退与认知衰退有关. 国家卫生研究院工具箱气味识别测试 (NIHTB-OIT) 显示,西班牙语老年人的表现因年龄,性别和认知状况而异.

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科学领域:

  • 神经科学是一个神经科学.
  • 老年学是一门学科.
  • 心理测量 心理测量 心理测量

背景情况:

  • 嗅觉衰退与老年人群的认知障碍有关.
  • 国家卫生研究院工具箱气味识别测试 (NIHTB-OIT) 是一种经过验证的嗅觉功能的测量方法.
  • 在拥有更高阿尔茨海默病风险的西班牙语和拉丁裔人口中,对NIHTB-OIT的验证至关重要.

研究的目的:

  • 评估NIHTB-OIT在西班牙语老年人横截面样本中的表现.
  • 评估嗅觉能力,年龄,性别和认知状态 (正常控制,轻度认知障碍,阿尔茨海默氏症类型痴呆症) 之间的关系.
  • 为了确定测试在多样化,有风险的人群中的实用性.

主要方法:

  • 一项对239名西班牙语成年人 (53-89岁) 的横截面研究,包括正常对照 (NC),轻度认知障碍 (MCI) 和阿尔茨海默氏症类型痴呆症 (DAT) 组.
  • NIHTB-OIT的管理由经过培训的考官使用抓取和嗅探卡.
  • 使用ANOVA和Welch Two样本t测试进行数据分析,以检查年龄,诊断,性别及其相互作用的影响.

主要成果:

  • 在NIHTB-OIT得分上观察到年龄,诊断和性别的重大主要影响.
  • 老年人和有认知障碍的人通常得分较低.
  • 在健康的老龄化个体中发现了性别差异,女性得分更高;年龄,性别和认知状态之间的三向相互作用是显著的.

结论:

  • 根据NIHTB-OIT的数据,西班牙语老年人基于认知状态和性别的差异性表现.
  • 研究结果表明,随着这个人群的老龄化,嗅觉衰退的临床表现异构.
  • 该研究强调了在认知衰老研究的嗅觉评估中考虑人口因素的重要性.