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概括
此摘要是机器生成的。

基于平板电脑的认知评估工具 (TabCAT) 有效地识别了撒哈拉以南非洲的认知障碍 (CI),包括艾滋病毒感染者 (PLWH). 这种数字工具显示出在不同人群中广泛使用的前景.

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科学领域:

  • 神经学 神经学
  • 老年学是一门学科.
  • 传染性疾病 传染性疾病

背景情况:

  • 撒哈拉以南非洲 (SSA) 正经历着人口变化,老年人,艾滋病毒感染者 (PLWH) 的数量越来越多,阿尔茨海默氏症 (AD) 的流行率越来越高.
  • 该地区在诊断认知障碍 (CI) 方面面临重大挑战,原因是缺乏医疗保健专业人员和缺乏文化相关的评估工具.
  • 基于平板电脑的认知评估工具 (TabCAT) 提供了一个潜在的解决方案,它是一个简短的,数字管理的电池,具有适合不同人群的自动评分.

研究的目的:

  • 评估基于平板电脑的认知评估工具 (TabCAT) 在撒哈拉以南非洲 (SSA) 背景下识别认知障碍 (CI) 的性能和有效性.
  • 评估TabCAT在涉及老年人,包括艾滋病毒感染者 (PLWH) 和乌干达艾滋病毒未感染者的前性队列研究中的实用性.
  • 确定TabCAT是否是SSA多元文化背景,语言和教育水平的认知评估的可靠工具.

主要方法:

  • 通过专家审查和重点小组,TabCAT经历了翻译和文化适应.
  • 将TabCAT得分与在乌干达使用的经过验证的参考标准认知测试电池进行了比较.
  • 该研究采用了根据年龄,性别和教育情况调整的Z-score,并使用了Jak/Bondi标准来定义CI. 接收器运行特征 (ROC) 曲线评估了区分能力.

主要成果:

  • 从当地专家和重点小组来看,TabCAT表现出可接受的面部和内容有效性.
  • 这项研究包括563名参与者 (平均年龄60岁,50%为女性,51%不到小学教育,49%为PLWH).
  • TabCAT复合得分在识别CI (c-统计值0.79) 中表现良好至出色,在艾滋病毒感染者 (PLWH) 中表现类似.

结论:

  • TabCAT显示了在撒哈拉以南非洲人口中检测CI的内容,并发和标准有效性,包括PLWH.
  • 尽管同时有效性存在一些变化,但TabCAT是用于CI识别的有希望的简短工具,适用于不同的人口统计和艾滋病病毒状态.
  • 计划进行进一步的研究,以探索TabCAT在乌干达和类似资源有限的环境中诊断阿尔茨海默病 (AD) 和相关痴呆症的有效性.