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Updated: Jan 7, 2026

Immunopeptidomics: Isolation of Mouse and Human MHC Class I- and II-Associated Peptides for Mass Spectrometry Analysis
09:32

Immunopeptidomics: Isolation of Mouse and Human MHC Class I- and II-Associated Peptides for Mass Spectrometry Analysis

Published on: October 15, 2021

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免疫基组学与全长转录组学相结合,揭示了各种各样的新抗原

Takamasa Ishino1, Tomofumi Watanabe2, Serina Tokita3

  • 1Department of Tumor Microenvironment, Okayama University, Graduate School of Medicine Dentistry and Pharmaceutical Sciences, Okayama 700-8558, Japan; Division of Cell Therapy, Chiba Cancer Center Research Institute, Chiba 260-8717, Japan; Department of Gastroenterology, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan.

Cell reports
|December 25, 2025
PubMed
概括

这项研究揭示了比以前更广泛的新抗原,对癌症免疫力和免疫疗法的有效性至关重要. 先进的测序方法发现了新的新抗原候选者,改善了我们对抗瘤反应的理解.

关键词:
CP: 癌症 癌症 癌症CP: 免疫学 免疫学在HLA结合体中,有HLA结合体.癌症免疫学 癌症免疫学已经耗尽的T细胞.长时间读取的RNA测序.新抗原是一种新抗原.一个单细胞RNA测序.一个单细胞TCR测序.

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