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Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
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药物开发 药物开发

Margarita Shedenkova1, Diana Salikhova1, Anastasia Nekrasova2

  • 1RUDN University, Moscow, Moscow, Russian Federation.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 25, 2025
PubMed
概括

人类质前代细胞衍生的细胞外囊泡 (EVs) 显示出对谷氨酸激发毒性的神经保护作用,谷氨酸激发毒性是阿尔茨海默病的关键因素. 这些EV激活PI3K-Akt信号通路,提供一种潜在的治疗策略.

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