Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Blood Studies for Cardiovascular System I: Cardiac Biomarkers01:20

Blood Studies for Cardiovascular System I: Cardiac Biomarkers

749
Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
749
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers01:19

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers

516
Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
516

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

The regulatory activities of plant microRNAs: a more dynamic perspective.

Plant physiology·2011
Same author

Complete genome sequence of the type strain Pseudomonas stutzeri CGMCC 1.1803.

Journal of bacteriology·2011
Same author

MyBioNet: interactively visualize, edit and merge biological networks on the web.

Bioinformatics (Oxford, England)·2011
Same author

Understanding lignin-degrading reactions of ligninolytic enzymes: binding affinity and interactional profile.

PloS one·2011
Same author

[The expression and significance of Notch1 in the human kidney tubular cell transdifferentiation induced by TGF-β(1);].

Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology·2011
Same author

Construction of microRNA- and microRNA*-mediated regulatory networks in plants.

RNA biology·2011

相关实验视频

Updated: Jan 7, 2026

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
07:20

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

Published on: January 28, 2014

37.1K

生物标志物 生物标志物

Yang Lü1, Ming Chen1, Wenbo Zhang1

  • 1The First Affiliated Hospital of Chongqing Medical University, Chongqing, Chongqing, China.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 25, 2025
PubMed
概括
此摘要是机器生成的。

这项研究揭示了正常认知,轻度认知障碍和阿尔茨海默病中明显的前额叶皮层功能连接模式. 左背侧PFC连接对于认知障碍至关重要,像BA45.R这样的特定区域区分轻度障碍.

更多相关视频

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

7.9K
Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans
08:14

Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans

Published on: April 28, 2023

702

相关实验视频

Last Updated: Jan 7, 2026

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
07:20

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

Published on: January 28, 2014

37.1K
Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

7.9K
Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans
08:14

Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans

Published on: April 28, 2023

702

科学领域:

  • 神经科学是一个神经科学.
  • 认知神经学 认知神经学
  • 医疗成像医学成像

背景情况:

  • 研究前额叶皮层 (PFC) 中的神经网络连接对于理解认知衰退至关重要.
  • 在早期干预中,区分正常认知 (NC),轻度认知障碍 (MCI) 和阿尔茨海默病 (AD) 是必不可少的.

研究的目的:

  • 通过使用功能近红外光谱学 (fNIRS) 在NC,MCI和AD组中比较PFC中的静止状态功能连接性 (FC).
  • 探索这些群体中PFC FC和认知子域之间的关系.

主要方法:

  • 休息状态fNIRS在328名参与者 (78名NC,121名MCI,129名AD) 上使用.
  • 分析了布罗德曼区域 (BA) 之间的功能连接.
  • 多变量逻辑和线性回归研究了认知领域和FC之间的关联.

主要成果:

  • 与NC和MCI组相比,阿尔茨海默病患者在PFC中显示出更高的平均HbO2水平.
  • 在几个BA对中的组之间发现了FC强度的显著差异,包括BA46.L-BA45.R和BA9.L-BA1.L.L.
  • 在BA45.R中,FC强度是区分MCI和NC的关键,特别是在休息状态的前2-3分钟内.

结论:

  • 静止状态的PFC FC强度在不同的认知水平上有很大差异.
  • 左背侧PFC区域 (BA46.L,BA9.L) 是认知障碍中皮质功能障碍的关键指标.
  • 特定的时间窗口和BA区域,如BA45.R,对于识别早期认知变化很重要.