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在脑瘤的功能性脑映射过程中,使用手术内电皮质学装置进行人工信号检测

William O Tatum¹, Adrian Safa², Filippo Colella¹

¹Department of Neurology, Mayo Clinic, Jacksonville, FL, USA.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology

|December 25, 2025

概括

高密度圆形网格通过检测具有较低刺激电流的更多工件和后放电 (ADs) 来改善手术内电皮质谱 (iECoG) 以绘制功能性大脑地图,从而提供更高的灵敏度和可解释的接触.

科学领域:

神经外科神经外科
神经生理学神经生理学
医疗器械医疗器械

背景情况:

术内电皮质谱 (iECoG) 对于功能性大脑映射 (FBM) 是至关重要的.
信号检测性能因电极配置而异.
优化电极选择可以提高手术精度和患者的治疗结果.

研究的目的:

为了比较循环电网与条带电极在FBM的iECoG期间的信号检测性能.
评估每个电极类型在检测刺激器件和生理信号 (如放电后信号) 中的灵敏度.

主要方法:

对142名患者的iECoG记录的回顾性评估,这些患者接受了FBM的清醒骨切除术.
循环网格和线性条带电极之间的信号检测的比较.
刺激器件,放电后 (ADs) 和形活动的分析.

主要成果:

与条形电极相比,圆形电网显示出更高的信号幅度,检测到更多的后放电 (ADs) (59.2%与40.8%相比).
需要较低的刺激电流来唤起具有圆形网格的刺激工件,这表明灵敏度增加.
圆形网格的每次刺激的AD率显著更高 (率比为2.51).

结论:

高密度的圆形网格增强了手术期间对文物和ADS的检测.
圆形网格为功能大脑绘图提供了更高的灵敏度和更易于解释的联系.
这些发现支持使用圆形网格来改进iECoG信号检测.

关键词:

人工制品的艺术品.电刺激是一种电气刺激.电皮质谱学电皮质谱学电皮质谱学高密度的高密度的发作大脑映射发作大脑映射

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