在广泛的参考人群中,CMR衍生的左心室填充压的预测值
Ahsan A Khan1, Steven Dykstra1, Jacqueline Flewitt1
1Stephenson Cardiac Imaging Centre, University of Calgary, Calgary, Alberta, Canada; Libin Cardiovascular Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada; Department of Cardiac Sciences, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
心血管磁共振衍生的左心室填充压力 (LVFPcmr) 预测了不同患者群体未来的心力衰竭的结果. 18mmHg或更高的LVFPcmr是增加风险的重要指标.
科学领域:
- 心脏病学 心脏病学
- 医疗成像医学成像
- 心脏衰竭研究研究
背景情况:
- 心血管磁共振 (CMR) 衍生的左心室填充压力 (LVFPcmr) 显示为预后标志物具有前途.
- LVFPcmr与侵入性测量相关性很好.
研究的目的:
- 评估LVFPcmr与未来心力衰竭 (HF) 结果之间的关联.
- 将这些关联按左心室喷射率 (LVEF) 子组分层.
主要方法:
- 从卡尔加里心血管成像登记处 (2015-2021) 分析了9588名患者.
- 随访HF住院,心脏移植或LV辅助器件植入.
- 计算性别特定的LVFPcmr.
主要成果:
- LVFPcmr显著预测了HF结果 (次分布HR:Q3对Q1的1.988;P<0.001).
- 为LVFPcmr确定了18 mm Hg的最佳切割点.
- 在所有LVEF亚组中,LVFPcmr ≥18 mm Hg独立预测的结果.
结论:
- LVFPcmr是未来HF结果的强有力的预测器.
- 这一发现适用于广泛的转诊群体,包括具有维护,轻度减少和减少LV功能的群体.
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