Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Blood Studies for Cardiovascular System I: Cardiac Biomarkers01:20

Blood Studies for Cardiovascular System I: Cardiac Biomarkers

749
Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
749
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers01:19

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers

516
Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
516

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Combined inhibition of BETs and HDACs as a potential epigenetics-based therapy for malignant rhabdoid tumor.

Cell death & disease·2026
Same author

A multi-label cascade flexible neural forest model for predicting the subcellular location of multi-site bacterial proteins.

Scientific reports·2026
Same author

Targeting DNGR-1 with Fangchinoline Elevates Dendritic Cell Antigen Cross-Presentation-Mediated Antitumor Immunity in Melanoma.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
Same author

Extracellular vesicles of human transformed skin-derived precursors containing miR-221-3p promote hair growth through DKK2-mediated Wnt/<i>β</i>-catenin signaling.

Bioengineering & translational medicine·2026
Same author

Ameliorative effect of Polygonatum cyrtonema Hua polysaccharide on HFD/STZ-induced type 2 diabetes mice via improving gut microbiota imbalance and glucose metabolism disorder.

International journal of biological macromolecules·2026
Same author

NOTCH3 signal activation by its extracellular domain accumulation in an iPSC line newly established from a CADASIL patient.

Human cell·2026
Same journal

Evidence for progressive neurodegeneration in iatrogenic cerebral amyloid angiopathy.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Human brain connectome profiles mediate the relationship between pathology burden and clinical phenotypes in Alzheimer's disease.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Kat5 cKO mouse replicates biological domain signatures associated with Alzheimer's disease.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Evaluation of CSF and plasma tau species as fluid surrogate candidates for tau PET in prodromal to moderate Alzheimer's disease.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Associations of self-reported obstructive sleep apnea with cognition and dementia risk in cognitively unimpaired middle-aged adults.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Inflammation profiles in Alzheimer's disease relate to cognition and neurodegeneration.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
查看所有相关文章

相关实验视频

Updated: Jan 7, 2026

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
07:20

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

Published on: January 28, 2014

37.1K

生物标志物 生物标志物

Zhen Liu1, Dai Shi2, Anqi Li3

  • 1Institute of Neurological and Psychiatric Disorders, Shenzhen Bay Laboratory, Shenzhen, Guangdong, China.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 25, 2025
PubMed
概括
此摘要是机器生成的。

在中国老年人中,存在较少的阿波蛋白E-ε4 (APOE-ε4) 载体. 然而,与美国人相比,APOE-ε4同位素显示出更大的阿尔茨海默病生物标志物变化,海马缩以及中国人的认知能力下降.

更多相关视频

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

7.9K
Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans
08:14

Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans

Published on: April 28, 2023

702

相关实验视频

Last Updated: Jan 7, 2026

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
07:20

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

Published on: January 28, 2014

37.1K
Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

7.9K
Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans
08:14

Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans

Published on: April 28, 2023

702

科学领域:

  • 神经科学是一个神经科学.
  • 遗传学 遗传学是一种遗传学.
  • 老年学是一门学科.

背景情况:

  • 阿波利波蛋白E-ε4 (APOE-ε4) 是阿尔茨海默病 (AD) 的重要遗传风险因素.
  • APOE-ε4同胞性可能代表AD的独特遗传形式.
  • APOE4对老龄化人口,特别是东亚人的影响需要进一步调查.

研究的目的:

  • 为了比较中国和美国老年人之间的APOE基因型频率和阿尔茨海默病 (AD) 风险.
  • 为了调查APOE-ε4同性是否导致东亚与高加索老龄化人口中更明显的AD生物标志物变化.

主要方法:

  • 在大湾区健康衰老大脑研究 (GHABS) 中APOE等位基因频率的比较,中国队列和阿尔茨海默氏病神经成像计划 (ADNI) 美国队列.
  • 对血生物标志物 (Aβ42/Aβ40,ptau217,ptau181,GFAP),海马体积和认知的年龄和性别匹配的参与者的分析.
  • 使用了通用线性模型,并计算了与APOE-ε3ε3.3.相对的APOE基因型的Cohen D效应大小.

主要成果:

  • 与美国参与者 (ADNI) 相比,中国老年人 (GHABS) 的APOE-ε3ε4和APOE-ε4ε4等位基因百分比较低.
  • 在临床组 (认知不受损,MCI,痴呆症) 中,GHABS参与者的APOE-ε3ε4和APOE-ε4ε4显著减少.
  • 在APOE-ε3ε3匹配的比较中,GHABS APOE-ε4ε4个体的血ptau217,ptau181,GFAP,海马体积减少和认知能力下降的异常比ADNI APOE-ε4ε4个体更明显.

结论:

  • 与美国老年人相比,中国人中APOE-ε4载体的患病率较低.
  • 在中国老年人中,APOE-ε4ε4同性对阿尔茨海默病的生物标志物,大脑结构和认知功能产生了更大的不利影响.
  • 这些发现突出了APOE-ε4等位基对AD病理生理学影响的种族特征.