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药物开发 药物开发

Samar Padder1, Jesus J Campagna1, Sujyoti Chandra1

  • 1University of California, Los Angeles (UCLA), Los Angeles, CA, USA.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 25, 2025
PubMed
概括

一种新的药物DL-218通过抵消阿波利波蛋白E4 (ApoE4) 的作用来增强神经保护性Sirtuin 1 (SirT1) 水平. 这种阿尔茨海默病 (AD) 治疗候选药物在临床前模型中改善了记忆力.

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