儿科脏创伤幸存者的创伤后高血压:基于人口的队列研究
Matthew T Parrish1, Swathi Raikot1, Amy Glasgow2
1Department of Surgery, Mayo Clinic, Rochester, MN.
Journal of pediatric surgery
|December 25, 2025
概括
与没有受伤的同龄人相比,患有型损伤的儿童随着时间的推移面临患高血压的风险更高. 长期监测对于这些患者来说至关重要,以管理损伤后潜在的高血压.
科学领域:
- 儿科脏病学 儿科脏病学
- 创伤外科 手术 创伤外科
- 流行病学 流行病学
背景情况:
- 由于有限的数据,儿童时刻突性损伤后的高血压并未得到充分了解.
- 描述这种情况对于有效的儿科后期护理至关重要.
- 这项研究调查了以人口为基础的儿童群体中患有突损伤的高血压发病率.
研究的目的:
- 为了确定患有突损伤的儿童与没有受伤的对照人群相比,患高血压的发病率是否更高.
- 在儿童中,鉴别突损伤后高血压的长期风险.
主要方法:
- 一个基于人口的注册表确定了0-21岁的患者,患有的脏创伤 (1976-2024年).
- 损伤的严重程度被分级 (AAST或放射科医生).
- 使用生存分析 (Kaplan-Meier,Log-Rank,Cox回归) 将高血压发生率与匹配的无损对照进行了比较.
主要成果:
- 分析了116名突性损伤患者;中位数随访时间为12年.
- 受伤患者在受伤5年和20年后出现高血压的发生率显著增加 (4%对1%,18%对7%,p=.014).
- 的损伤增加了患高血压的风险 (危险比率2.60,p=.018).
结论:
- 高血压的发生率随着时间的推移在患有突损伤的儿童中增加.
- 这种发生率超过了无伤匹配对照的发生率.
- 长期跟踪对那些经历了突性损伤的儿童至关重要.
相关概念视频
01:29Acute Kidney Injury II: Pathophysiology
840
Acute kidney injury (AKI) causes are categorized into three primary categories based on the location of the injury: prerenal, intrarenal (or intrinsic), and postrenal causes. This classification guides clinical management and illustrates how different pathways can impair kidney function.Etiology and Pathophysiology of Acute Kidney Injury1. Prerenal causesEtiology: Prerenal Acute Kidney Injury, the most common type, occurs when reduced blood flow to the kidneys decreases filtration capacity...
840
01:30Acute Kidney Injury IV: Diagnostic Studies and Prevention
242
Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
242
01:20Acute Kidney Injury V: Interprofessional Care
268
Acute Kidney Injury (AKI) requires a collaborative healthcare approach to restore renal function and prevent complications. Essential management strategies involve monitoring fluid and electrolyte balance, adjusting medications, initiating dialysis when necessary, and providing nutritional support.Fluid and Electrolyte ManagementFluid Monitoring: Regularly monitoring body weight, central venous pressure, and urine output helps detect fluid imbalances early. Patient intake and output are...
268
01:22Acute Kidney Injury VI: Nursing Management
359
Acute Kidney Injury (AKI) results in an inability to maintain fluid, electrolyte, and acid-base balance. Effective nursing management is critical in improving patient outcomes and includes comprehensive patient assessment and targeted interventions.Comprehensive Patient AssessmentA detailed history collection is essential, focusing on any recent infections, nephrotoxic medication use, or chronic conditions such as hypertension and diabetes that may contribute to AKI. During the physical...
359
01:22Acute Kidney Injury I: Introduction
511
Introduction:Acute Kidney Injury (AKI) describes a swift decrease in kidney function occurring over hours to days, characterized by the kidneys' failure to remove waste products from the bloodstream. This leads to dangerous complications like metabolic acidosis, fluid overload, and electrolyte imbalances, such as hyperkalemia, which can cause life-threatening arrhythmias. AKI is common in both hospital and outpatient settings, often triggered by dehydration, sepsis, or exposure to nephrotoxic...
511
01:18Hypertension and Regulation of Blood Pressure
3.6K
Hypertension, the most common cardiovascular disease, is diagnosed through repeated measurements of elevated blood pressure. Its risks, including damage to the kidney, heart, and brain, are directly proportional to blood pressure levels. Starting from 115/75 mm Hg, the risk of cardiovascular disease doubles with each increment of 20/10 mm Hg. The diagnosis relies on blood pressure measurements, not on patient symptoms, as hypertension is often asymptomatic until end-organ damage is imminent or...
3.6K