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Updated: Jan 7, 2026

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
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药物开发 药物开发

Gregory M Cole1,2,3, Cansheng Zhu1,3, Kapil Manglani3,4

  • 1Veterans Greater Los Angeles Healthcare System, Los Angeles, CA, USA.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 25, 2025
PubMed
概括

一种新的药物,CNS11g,有效地减少了与帕金森病类似症状的小鼠的运动缺陷和有毒蛋白质聚合物. 这种口服治疗显示出对α-synuclein和tau oligomers的安全性和有效性,为synucleinopathies和阿尔茨海默病提供了希望.

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